The only temptation I know of in the bible concerning Jesus was when in the wilderness with the devil. A friend used Mel Gibson's Passion of the Christ as his basis to claim Jesus was tempted by the devil (with the appearance of a snake) while praying.
I kind of thought, personally that it made sense to why he needed the disciples to help him in prayer. He had to go back for the third time to pray with sorrow and heaviness untill an angel came to strengthen him.
"And there appeared an angel unto him from heaven, strengthening him. And being in an agony he prayed more earnestly: and his sweat was as it were great drops of blood falling down to the ground." (Luke 22:43-44).
Is it a mere spiritual reason to this claim that he was strengthened by an angel from heaven as if in a struggle or there are actual biblical references that support a spiritual encounter with the devil? If there was an encounter, how and why?