In general, Wisdom can be (and is, and was) identified as Jesus. However, there is this verse:

Proverbs 8:22 (NLT)
22 "The Lord formed me from the beginning,
         before he created anything else."

Hold on a moment...I thought God the Son wasn't created, having coexisted with God the Father since before time? How is the identity of Wisdom established as being that of the Son and how is Proverbs 8:22 handled? If it makes a difference, I grew up Wesleyan, so I'd prefer Protestant doctrines although Catholic or Orthodox doctrines are acceptable.