@DanFefferman, "I would like to see answers about what readers learned from the book" - why would a Christ follower read such a book in the first place? It's nonsense. Scripture is explicitly clear Jesus first coming was a propitiation for sin not a government uprising. The prophets spoke of it centuries before it happened.

@FShrike it does not matter what social and culture distinguish. The Word of God is very straightforward and makes no such distinction between the two. There are two genders. A person is born of one of the two. If they identify as something else they're in need of the Lord and reality.

@user253751, "pray to see" is acceptable. That's to gain function for the body God gave the man - not praying to change his gender/identity which is definitely not within God's will.

@user253751, if one's sexual "identity" is different than their gender, it's a figment of one's imagination. A person's gender is reality regardless of who/what they identify as.

@FShrike, it couldn't be more plain in scripture: there are two genders, male and female. "Man or woman" conveys the same idea.

The fault of the question lies here, "but please take the premise seriously", because the book's premise is nonsense. The short answer to your bullet points is Jesus Christ is saving us from ourselves. It is our nature that causes our fallen state. Those without that insight framed it in worldly terms like government, power, etc. which is His Second Coming. Scripture prophesied He was both a lion and a lamb. His first coming was the lamb, a propitiation for sin and His Second Coming will be as the lion, c.f. Day of the Lord in scripture.

@curiousdannii, "So what's the big issue?" is stated in the question. :-)