We know from the Bible that Judas was not meant to be saved. So, the answer would have to be yes. > "While I was with them, I protected them and kept them safe by that name you gave me. None has been lost except the one doomed to destruction so that Scripture would be fulfilled." -- John 17:12 (NIV) Whether or not everyone is predestined to either go to Heaven or to Hell prior to birth is a matter of debate with no clear answer (the answer either way is only clear to the believer). However, none can dispute the fact that, according to the Bible, some have been and more may be. Some argue that this was not referring to Judas, as the literal translation of the "one" (from the NIV translation) from the Greek υἱός ἀπώλεια is "son of perdition", but rather this was referring to the devil. However, this would have to be inaccurate in this context. By the time that Jesus said these words, Judas had already accepted the money from the Sanhedrin, and "satan had already entered him" (John 13:27). By the fact that satan had entered Judas, and shortly after (and before the resurrection) Judas went and hung himself, he would have been lost. In order to support the position that this verse is referencing Satan, one must posit that Judas was saved, despite the presence of Satan in him. Otherwise, Christ was in error saying that "None had been lost". Otherwise, regardless of whether the verse was specifically referencing Judas or Satan, Judas had not been given to Christ to save, and thus had been doomed to destruction.