Dale Tuggy, a Biblical Unitarian, discusses the Apostles' Creed in this podcast. He says
"The creed has been called 'Trinitarian', in that it starts with the
Father, then moves on to the Son, then finally to the Holy Spirit. But
it doesn't so much as hint that these three are one God, or say that
they are equally divine persons within one God. The creed presupposes
monotheism and it two times tells us who the one God is. It is the
Father Almighty. It presupposes, then, that the one God is not the
three of them put together, as Trinitarian theories have it. We also
don't see here what is nowadays called the doctrine of the deity of
Christ, we don't see the claim that Christ has two natures - a human
nature and a divine nature. Nor does it mention Christ's eternal
generation from the Father or even his existence before his human
life. The Holy Spirit just gets a brief mention. The Holy Spirit is
not asserted to be personal or to be a divine person equal to the
Father and the Son, nor is the Spirit's eternal generation from the
Father and the Son mentioned. The reason the creed doesn't mention
these things is that when the creed was first written - or perhaps
when its ancestor documents were first written - these things were not
So vis a vis Trinitarianism, this creed does not seem to present a problem for a Biblical Unitarian, despite a so-called 'Trinitarian structure', whatever that means exactly.
However, Tuggy does go on to raise concern about the phrase "descended to the dead", suggesting it is based on a slight scriptural basis and perhaps misleading (see @SteveOwen's answer), and the phrase "The holy catholic church" which, he claims, in its original sense might have been churches with Bishops, and nowadays would be limited to certain churches derived from those, although Protestants often interpret this phrase as meaning the body of Christ - i.e., all Christians that form a universal 'church'.
So, I think the answer is that the creed is fine for Biblical Unitarians, as much as it is for Protestants in general, i.e., some might have reservations about a couple points, but these aren't dependent on Trinitarian considerations in particular.