Is prayer supposed to be the unique means of accepting God's will under Catholic theology? How is a good Catholic supposed to overcome resistance to or confusion about God's will? What do key theologians have to say?
St. Thomas Aquinas's prayer "Concede mihi, misericors Deus" includes the request "quod a me requiris, ut faciam, tribue ut sciam" ("grant that I may know what you require me to do"). (See, for example, http://www.preces-latinae.org/thesaurus/Varia/Concede.html)
If the greatest theologian of the last millennium felt the need to make that request, it shouldn't be surprising that God's will for the rest of us may also be difficult to discern. We may need to deploy all the tools at our disposal, including our own intelligence, prayer, reading, and consultation with others.