It's well known that Protestants reject the doctrine of Intercession of Saints. According to Wikipedia:
With the exception of a few early Protestant churches, most modern Protestant churches strongly reject the intercession of the dead for the living, but they are in favor of the intercession of the living for the living according to Romans 15:30.
When it comes to arguing for the rejection of the doctrine of Intercession of Saints (specifically, the intercession of the dead for the living), what are the strongest apologetic arguments according to Protestants? Are there compelling reasons that should be able to dissuade any rational believer from seeking intercession support from departed Saints?
Note: the counterpart question can be found at What are the strongest apologetic arguments in defense of the veracity of the doctrine of Intercession of Saints?