To clarify, this question is not asking for a "justification" of those times, described in the Bible, when God struck someone dead. Life is His to take. the question is also not asking strictly ...
If the Holy Spirit is God, and God can not be in the presence of sin, then how can the Holy Spirit dwell in me a sinner?
If we believe in the Trinity, in essense that the Holy Spirit is God, and we believe that God can not be in the presence of sin, then how can the Holy Spirit dwell within me a sinner?