I myself has always been partial to the line from the movie "Constantine:"
Angela Dodson: I guess God has a plan for all of us.
John Constantine: God's a kid with an ant farm, lady. He's not planning anything.
Now John's a cynic, and not a believer. In fact, at this point in the film he's about as un-sympathetic as possible without actually being the bad guy, with that line as one of the "cappers." But that doesn't mean it's not my answer.
God created us and gave us this place. It's ours, and we do with it what we like. If we build an interstate, it stays built; if we discover a vaccine, it keeps working; if we execute an innocent man, with one notable exception, he stays dead.
Some people stop there and claim then that there's no need for God, or even no room for God. But that isn't true. For starters, God isn't a child and this isn't an ant farm. He works on this planet, but not by stepping in and fixing it for us, but by working through us. Like a loving father, just because he "gave" it to us doesn't mean that he doesn't want to see us make the best of it.
And so we have the prophets, and the Incarnation, and the Spirit. Not to take it out of our hands and "fix it," but to show us the ways to make it better and to enable us to do so.
And, ultimately, I do believe God has a plan. A big one, bigger than we can possibly imagine. But I've sat through too many funerals and tragedies where "it's God will" was repeated to the point of desperate chanting, or poems read about why he sometimes picks the youngest flowers to pretty up his home, a phenomenon Rick Diamond calls "God the Monster." And I'm with him in saying: please stop saying that: "Just tell them you love them and your sorry this happened. That's enough."
After my mom's friend drowned in a riptide, there much of that. He was a well-beloved missionary and family man who was known for his kindness. And there was much "we don't know why this happened." And during that, I realized I did: loving God and ones family doesn't give someone the ability to breathe underwater. That's what makes riptides dangerous to everyone. And then I could start to mourn him.
After that, I stopped blaming God for not saving us from ourselves. The problems we have as a world, we have because we haven't solved them yet. The evil is that we let our own short-sighted self-interest and fear keep us from solving them. God is at work within us to correct that, if we will let him.
And that's how I would respond, but that's just my answer.