Transsexualism is a phenomenon experienced by individuals who transition between either of the two major sexes, male and female, not due to social pressures or mental disorders, but due to an acute feeling of fundamental discontent with the sex to which they have been assigned (gender dysphoria).
Neuroscience studies of transsexuals in recent years are increasingly suggesting that transsexuality is a biological phenomenon rather than a purely psychological one, as transsexuals' brain structures tend to have a strong resemblance to the brains of their identified gender, even before beginning sex reassignment therapy.
While there is no "gay gene" , there exist "transsexual gene."
Australian researchers have identified a significant link between a
gene involved in testosterone action and male-to-female
transsexualism.DNA analysis from 112 male-to-female transsexual
volunteers showed they were more likely to have a longer version of
the androgen receptor gene.The genetic difference may cause weaker
testosterone signals, the team reported in Biological Psychiatry.
The Bible does not explicitly say anything about the issue of transsexualism (Gender Dysphoria) but like in other issues not written, we need to address this issue in light of the Bible as a whole.
Biblical Explanation of the cause:
Premise 1: God created each and every one of us in the womb ( Psalm 139:13)
Premise 2: This sort of creation is in line with the effects of sin because it is within the realm of Post-Adamic fall ( Genesis 3, Romans 8:22).
Premise 3: People afflicted with Gender Dysphoria (Transsexualism), a disorder (John 9:3)
Premise 4: There are only two sexes which is also two genders per se( man/woman) –Genesis 1:26-27)
Conclusion: Transsexualism is a medical condition because it is a birth defect per se and requires treatment/cure per 3 John 1:2.
Is Reparative Theraphy for transsexuals an effective treatment for Gender Dysphoria?
“Treatment aimed at trying to change a person’s gender identity and expression to become more congruent with sex assigned at birth has been attempted in the past without success (Gelder & Marks, 1969; Greenson, 1964), particularly in the long term (Cohen-Kettenis & Kuiper, 1984; Pauly, 1965). Such treatment is no longer considered ethical.” — Medical Standards of Care v7 2011
Is Gender Reassignment an effective treatment for Gender Dysphoria?
"Gender reassignment (which includes psychotherapy, hormonal therapy and surgery) has been demonstrated as the most effective treatment for patients affected by gender dysphoria (or gender identity disorder), in which patients do not recognize their gender (sexual identity) as matching their genetic and sexual characteristics." (http://www.ncbi.nlm.nih.gov/pubmed/21487386).
1 Corinthians 10:23 (NLT)
You say, "I am allowed to do anything"--but not everything is good for
you. You say, "I am allowed to do anything"--but not everything is
Gender Reassignment is allowable because it is good and beneficial for the afflicted of Gender Dysphoria.
In fact, we Christians (disciples of Christ) cannot judge Transsexuals due to the fact of XX male syndrome and XY female syndrome.Transsexualism is therefore a very private issue that should be a matter between God and the afflicted (Romans 14:4).