Most non-Catholic denominations do not believe in the perpetual virginity of Mary, and fully accept the idea of Jesus having biological half-brothers. (Only He has God for a Father.)
From a perspective of Sola Scriptura, there's no support for the idea that Mary remained a virgin through life, and there is Biblical evidence that Jesus had brothers.
*Please do not take the following quote as me endorsing a view that rejects or accepts the perpetual virginity of Mary. I'm including it to support the paragraph above.
So, what does the Bible say about the perpetual virginity of Mary?
Using the New American Bible, which is a Catholic translation, we can
see that the perpetual virginity of Mary is not taught in the Bible.
Matthew 1:25 NAB tells us, "He had no relations with her until she
bore a son, and he named him Jesus." He, Joseph, did not have sexual
relations with her, Mary, UNTIL after she bore a son, Jesus." The
meaning of this Scripture is abundantly clear. Joseph and Mary did not
have sexual relations until after Jesus was born. Matthew 13:55-56 NAB
declares, "Is He not the carpenter's son? Is not his mother named Mary
and his brothers James, Joseph, Simon, and Judas? Are not His sisters
all with us?" Catholics claim, correctly, that the Greek terms for
"brothers" and "sisters" in these verses could also refer to male and
female relatives, not necessarily literal brothers and sisters.
However, the intended meaning is clear, they thought Jesus to be
Joseph's son, the son of Mary, and the brother of James, Joseph,
Simon, and Judas, and the brother of the unnamed and unnumbered
sisters. Father, mother, brother, sister. It is straining the meaning
of the text to interpret “brothers” and “sisters” as "cousins" or
"relatives" with the mentioning of Jesus' mother and father.
However, there are Protestant denominations that still accept the doctrine of the Perpetual Virginity of Mary.
The view on whether Jesus had biological brothers is, therefore, varied, and the view hinges on whether or not you accept that doctrine.
For more on Protestant views on the doctrine of perpetual virginity, see What do Protestants say was the source for the doctrine of the perpetual virginity of Mary?